Respiratory

August 12, 2022

The IISc Finds A Novel Inhibitory Action of Montelukast Against the SARS-CoV-2 Virus

Montelukast administration lead to significantly fewer events of clinical deterioration in hospitalized COVID-19 patients and repurposing Montelukast for tackling cytokine storms in COVID-19 patients has been suggested. A recent study by the Indian Institute of Science (IISc) investigated the anti-viral activity of several FDA approved agents including Montelukast against the SARS-CoV-2 virus.

Newer evidence coming from IISc suggests that Montelukast can be used as a lead molecule to design potent inhibitors against SARS-CoV-2.

SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2, IISc: Indian Institute of Science, COVID-19: Coronavirus disease 2019, From the Makers of:
Nsp1: Non-structural protein 1.

References:

Afsar M, Narayan R, Akhtar MN, Das D, Rahil H, Nagaraj SK, Eswarappa SM, Tripathi S, Hussain T. Drug targeting Nsp1-ribosomal
complex shows antiviral activity against SARS-CoV-2. Elife. 2022 Mar 24;11:e74877.

253

Short-Term Exposure to Secondhand Smoke Has Significant Effects on Asthmatic Patients

Patients Admitted for Asthma Exacerbations are Predominantly Obese and Have Poor Asthma Control at Baseline

Initiation of Mepolizumab in Severe Eosinophilic Asthma Reduces Usage of Oral and Inhaled Corticosteroids

Are Specific Types of Bacteria Related To Acute Exacerbations in Children with Asthma?

High Prevalence of Respiratory Symptoms after COVID-19 is Associated with Disease Severity Markers

Increased Patient Awareness of Chronic Obstructive Pulmonary Disease is Associated with Increased Adherence to Treatment

Hypertensive Disorders in Pregnancy Increase the Risk of Asthma in Offspring

Yoga Has Significant Positive Effects on Asthma Control in Children

Understanding the Differences of Clinical Outcomes Between Elderly and Adult Patients with Allergic Rhinitis

Can Montelukast Sodium Combined with Budesonide Aerosol Improve Airway Function in Asthmatic Children?

Treatment-Seeking Behavior of Young Hypertensives in India: An Analysis of NFHS-4

Risk Factors Accelerating Time-to-Diagnosis of COPD among Asthma Patients

As-needed Vs Maintenance Regimens in Mild Asthma – Patient Perspectives

Can Digital Mindfulness-based Interventions Improve Asthma-related QoL?

What are the Different Risk Factors Associated with Persistent Chronic Cough?

Procalcitonin, C-Reactive Protein and White Blood Cell Levels Help to Differentiate Acute Bacterial or No-Bacterial Infections in Children

Severe Asthma/Asthma Exacerbations Before Pregnancy Can Increase Rate of Exacerbations During Pregnancy

Exercise Rehabilitation Has Positive Effects on Children with Bronchial Asthma

Inhaled Corticosteroids Can Be Used as a Measure of Adherence in Severe Asthma

Recurrent Lower Respiratory Tract Infections Are Associated With Earlier Diagnosis of Pediatric Asthma

Ciclesonide Effectively Improves Asthma Symptoms in Children

High Intensity Interval Training and Sprint Interval Training is Effective for Asthma Patients

Small-Airways Targeted Treatment with Smart Nebulizer Technology Reduces Asthma Exacerbations in Children

Low serum IgA levels in asthmatic patients with recurrent chest infections

Inhaler training can improve patients’ peak inhalation flow rate

Maternal Asthma Severity Associated With Higher Chance Of Adverse Perinatal Outcomes

The Effects of Smoking on Atopic and Non-Atopic Asthma Differ With Gender

Cardiorespiratory Endurance and Muscular Strength Are Not Reduced In Individuals with Asthma

Higher Intake of Preformed Vitamin A In Mid-Childhood Lowers Risk of Incident Asthma

Cookie Consent